Equinety is 100% safe to give with any other medications or supplements or feeds. The Equinety Horse XL is 100% pure amino acids which are the building blocks of protein. So as a matter of fact we encourage people not to change anything that they are doing and just add a scoop of Equinety to the product and this way it is the only element that you are changing. You will typically see results within a couple of weeks to thirty days. It is 100% safe to give with any other supplements or medications.